You can go to a user's topic by ~loginname instead of Main/FirstLast.
More specifically, if you open http://twiki.example.com/cgi-bin/view/~loginname, you are redirected to http://twiki.example.com/cgi-bin/view/Main/FirstLast.
If you are logged in TWiki, you can go to your topic merely by ~.
This is especially handy if login names are different from wikinames and shorter.
You can go to a topic of a user's subweb directly by e.g. http://twiki.example.com/cgi-bin/view/~loginname/WebPreferences
Combination with view URL shortening
If you are shortening view URLs (http://twiki.example.com/Web/Topic), you need to modify your URL rewriting rules so that ~ is recognized as a valid first character of a web name.
Then, you can go to your topic merely by http://twiki.example.com/~.
Related Topics:AdminDocumentationCategory, UserDocumentationCategory, UserSubwebs